Separation of particles in non-Newtonian fluids flowing in T-shaped microchannels

Background The flow of suspensions through channel bifurcations is a relevant topic in several applications such as microfluidics and biology. Indeed, a number of microfluidic devices consisting of a main channel with several side branches, aimed at separating particles with different size, has been proposed [1–4]. From the biological side, the microcirculatory network is made of many capillary bifurcations. The partitioning of red blood cells, white blood cells and platelets at vessel junctions plays an important role in determining the Abstract Background: The flow of suspensions through bifurcations is encountered in several applications. It is known that the partitioning of particles at a bifurcation is different from the partitioning of the suspending fluid, which allows particle separation and fractionation. Previous works have mainly investigated the dynamics of particles suspended in Newtonian liquids. Methods: In this work, we study through 2D direct numerical simulations the partitioning of particles suspended in non-Newtonian fluids flowing in a T-junction. We adopt a flow configuration such that the two outlets are orthogonal, and their flow rates can be tuned. A fictitious domain method combined with a grid deformation procedure is used. The effect of fluid rheology on the partitioning of particles between the two outlets is investigated by selecting different constitutive equations to model the suspending liquid. Specifically, an inelastic shear-thinning (Bird-Carreau) and a viscoelastic shear-thinning (Giesekus) models have been chosen; the results are also compared with the case of a Newtonian suspending liquid. Results: Simulations are carried out by varying the confinement, the inlet flow rate and the relative weight of the two outlet flow rates. For each condition, the fluxes of particles through the two outflow channels are computed. The results show that shearthinning does not have a relevant effect as compared to the equivalent Newtonian case, i.e., with the same choice of the relative outlet flow rates. On the other hand, fluid elasticity strongly alters the fraction of particles exiting the two outlets as compared to the inlet. Such effect is more pronounced for larger particles and inlet flow rates. Conclusions: The results illustrated here show the feasibility to efficiently separate/ fractionate particles by size, through the use of viscoelastic suspending liquids.